Academic Outputs

Journal Publications

  1. Tsiapalis, D., De Pieri, A., Biggs, M., Pandit, A., Zeugolis, D.I.* Biomimetic bioactive biomaterials – The next generation of implantable devices. ACS Biomaterials Science & Engineering, Vol. 3, No. 7, pp. 1172-1174 (2017). * Corresponding AuthorImpact Factor 2014: N/A
  2. Guillaumin, S., Sallent, I., Zeugolis, D.I.* Biophysics rules the cell culture but has yet to reach the clinic: Why is that? Journal of the American Academy of Orthopaedic Surgeons, Vol. 25, No. 7, pp. e144-e147 (2017). * Corresponding AuthorImpact Factor 2014: 3.055 
  3. Bach Q., Vasilevich A., Vermeulen S., Hulshof F., Stamatialis D., van Blitterswijk C., de Boer J. Micro-topographies promote late chondrogenic differentiation markers in the ATDC5 cell line. Tissue Engineering: part A 2017 (I.F.:3.892) (PMID: 28152670) 
  4. Kumari S.*, Vermeulen S.*, Carlier A., de Boer J and Subramanyam D. Shaping cell fate: influence of substratum properties on embryonic stem cells and their pluripotency. (2017) Submitted for publication * These authors contributed equally 
  5. De Pieri, A. *; Ribeiro, S.*; Tsiapalis, D. *; Eglin, D.; Bohner, M; Dubruel, P; Procter, P.; Zeugolis, D.I.; Bayon, Y.** Joint academic and industrial efforts towards innovative and efficient solutions for clinical needs. Journal of Materials Science: Materials in Medicine, Vol. 29, No. 8, pp. 129 (2018). *These authors contributed equally. *Corresponding Author. Impact Factor: 2.448
  6. Vermeulen S., Vasilevich A., Tsiapalis D., Roumans N., Vroemen P., Beijer N., Dede-Eren A., Zeugolis D.,  de Boer J. Identification of Topographical Architectures Supporting the Phenotype of Rat Tenocytes. Acta Biomaterialia 2018 (I.F.: 6.319)
  7. Leuning D., Beijer N., du Fosse N., Vermeulen S., Lievers E., van Kooten C., Rabelink T., de Boer J. The cytokine secretion profile of mesenchymal stromal cells is determined by the surface structure of the microenvironment. Scientific Reports 2018 (I.F.: 4.259) (PMID: 29769543)
  8. Pugliese, E., Coentro, J. Q., Raghunath, M., Zeugolis, D. I. Wound healing and scar wars. Advanced Drug Delivery Reviews. 2019. DOI: 10.1016/j.addr.2018.05.010
  9. Coentro, J.Q., Pugliese, E., Hanley, G., Raghunath, M., Zeugolis, D.I. Current and upcoming therapies to modulate skin scarring and fibrosis.  Advanced Drug Delivery Reviews. 2018. DOI: 10.1016/j.addr.2018.08.009
  10. Calejo I, Costa‐Almeida R, Gonçalves AI, Berdecka D, Reis RL, Gomes ME. Bi-directional modulation of cellular interactions in an in vitro co-culture model of tendon-to-bone interface. Cell Prolif. 2018; e12493.
  11. Costa-Almeida, R., Berdecka, D., Rodrigues, M.T., Reis, R. L., Gomes, M. E. Tendon explant cultures to study the communication between adipose stem cells and native tendon niche. J Cell Biochem. 2018; 119:3653-3662
  12. Ribeiro, S.; Ricci, M.; Von Der Lieth, A.; Bayon, Y.; Zeugolis, D.; Pelayo, S.; Marque, I. and Pazart, L. (2019). Empowering Translation of New Ideas – A EIT Health ClinMed Summer School Overview.In Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies – Volume 5: ClinMed, ISBN 978-989-758-353-7, pages 603-610. DOI: 10.5220/0007696606030610
  13. Escuder Tisaire, J.; Rodrigo, E.; Ribeiro, S.; Ricci, M.; Cuellar, J.; Zeugolis, D.; Bayon, Y. and Rocha, I. (2019). Concept Design of a New Portable Medical Device for Lymphedema Monitoring: A EIT Health ClinMed Summer School Project.In Proceedings of the 12th International Joint Conference on Biomedical Engineering Systems and Technologies – Volume 5: ClinMed, ISBN 978-989-758-353-7, pages 611-620. DOI: 10.5220/0007696706110620
  14. Ribeiro, S.; Fernandes, E.; Gomes, M.; Reis, R.; Bayon, Y. and Zeugolis, D. (2019). Design and Characterization of Synthetic Biodegradable Films for Soft Tissue Engineering.In Doctoral Consortium – Volume 1: DCBIOSTEC, ISBN , pages 28-32

Conference Papers

  1. Dede-Eren, A., Vermeulen, S., Hebels, D., de Boer, J. Molecular control of tenocyte phenotype through matrix-mediated mechanotransduction. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  2. Sallent, I., Zeugolis, D. I. The synergistic effect of topography and substrate rigidity in the development of a collagen scaffold for tendon tissue engineering. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  3. Guillaumin, S., Zeugolis, D. I. Tenogenic differentiation of mesenchymal stem cells (MSCs): a co-culture approach. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  4. De Pieri, A. Gorelov, A., Rochev, Y., Zeugolis, D. I. Thermoresponsive nanofibers for engineering extracellular matrix-rich tissue substitutes. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  5. Rampin, A., Skoufos, I., Tzora, A., Prassinos, N., Diakaki, N., Zeugolis, D. I. Engineering optimal culture conditions to maintain tenogenic phenotype. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  6. Dei, A., Chang, W., Sampaio, A., Zeugolis, D. I. Development of serum-free culture conditions for differentiation of bone marrow-derived mesenchymal stromal cells to tenocyte-like cells. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  7. Djalali-Cuevas, A.,  Skoufos, I., Tzora, A., Prassinos, N., Diakaki, N., Zeugolis, D. I. RNA-Seq and meta-profiling for a better understanding of the musculoskeletal system biology. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  8. Berdecka, D., Babo, P. S., Reis, R. L., Gomes, M. E. Effect of TGF-β3 and GDF-5 on the expression of tendon / ligament markers in human dental pulp stem cells and periodontal ligament cells. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  9. Garnica-Galvez, S., Skoufos, I., Tzora, A., Prassinos, N., Diakaki, N., Zeugolis, D. I. Assessment of novel macromolecular crowders to produce cell sheets for scaffold-free musculoskeletal tissue regeneration. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  10. Tsiapalis, D., Zeugolis, D. I. Α multi-factorial toolbox towards tenogenic phenotype maintenance. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  11. Pugliese, E., Korntner, S., Zeugolis, D. I. Multilayer collagen-based scaffold as delivery vehicles of bioactive molecules for the bone-to-tendon interface regeneration. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  12. Ribeiro, S., Fernandes, E., Gomes, M. E., Reis, R. L., Bayon, Y., Zeugolis, D. I. Design and characterization of synthetic biodegradable films for musculoskeletal tissue engineering. Podium Presentation at European Orthopaedic Research Society (EORS) Meeting, 25th to 28th of September 2018, Galway, Ireland.
  13. De Pieri, A., Gorelv, A., Rochev, Y., Zeugolis, D. I. Anisotropic thermoresponsive nanofibers for engineering extracellular matrix-rich living substitutes. Podium Presentation at 4th International Conference on Biomedical Polymers & Polymeric Biomaterials, 15 to 18 July 2018, Krakow, Poland.
  14. Pugliese, E., Bayon, Y., Zeugolis, D. I. Collagen-based devices as multi-cargo delivery vehicles for tendon treatmentsPodium Presentation at 4th International Conference on Biomedical Polymers & Polymeric Biomaterials, 15 to 18 July 2018, Krakow, Poland.
  15. Ribeiro, S., Novacek, V., Fernandes, E., Gomes, M., Reis, R. L., Bayon, Y., Zeugolis, D.I. Design and characterization of synthetic biodegradable films for tendon tissue engineeringPodium Presentation at 4th International Conference on Biomedical Polymers & Polymeric Biomaterials, 15 to 18 July 2018, Krakow, Poland.
  16. François, I, Sivelli, G., Schramme, M., Dudhia, J., Smith, R. K. Standardised histopathologic scoring system to assess tendon healing. Poster Presentation at TendonUK Meeting, 11th to 12th of April 2018, Oxford, United Kingdom.
  17. Sivelli, G., François, I, Smith, R. K., Dudhia, J. Characterisation of extracellular vesicles derived from equine msenchymal stem cells and tenocytes. Poster Presentation at TendonUK Meeting, 11th to 12th of April 2018, Oxford, United Kingdom.
  18. Tsiapalis, D.V., Monsonis-Capella, H., Zeugolis, D.I. Macromolecular crowding and low oxygen tension can stimulate tenogenic phenotype maintenancePoster Presentation at Matrix Biology Ireland (MBI) Meeting, 30th of November to 1st of December 2017, Dublin, Ireland
  19. Sallent, I., Gaspar, D., Zeugolis, D. The synergistic effect of topography and mechanical stimulation in the development of a tissue engineered tendon constructPoster Presentation at Matrix Biology Ireland (MBI) Meeting, 30th of November to 1st of December 2017, Dublin, Ireland
  20. De Pieri, A., Ryan, C.N.M., Spanoudes, K., Rochev, Y., Zeugolis, D.I. Biophysical cues to direct the in vitro tenogenic differentiation of mesenchymal stem cellsPoster Presentation at Matrix Biology Ireland (MBI) Meeting, 30th of November to 1st of December 2017, Dublin, Ireland
  21. Dede A., den Hartog T., Valster H., de Boer J. Decellularized tendon tissue as bioactive graft material. Poster Presentation at Netherlands Society for Biomaterials and Tissue Engineering, 29th to 30th November 2017, Lunteren, Netherlands
  22. Berdecka, D., Gonçalves A.I., Rodrigues, M. T., Reis, R. L., Gomes, M. E. Human adipose derived stem cells-in quest of subset prone to tenogenic induction. Poster Presentation  at Gene2Skin 2017 Winter School and Term Stem 2017- Forecast Conference, 13th to 17th November 2017, Porto, Portugal
  23. Ribeiro, S., Novacek, V., Fernandes, E., Gomes, M., Bayon, Y., Zeugolis, D.I. Design and characterization of biodegradable polymeric films for tendon tissue engineeringPodium Presentation at Future Investigators of Regenerative Medicine (FIRM) Meeting, 25th to 28thof September 2017, Girona, Spain
  24. Tsiapalis, D., Zeugolis, D.I. Microenvironmental cues to maintain tenogenic phenotype in vitroPodium Presentation at European Orthopaedic Research Society (EORS) Meeting, 13th to 15th of September 2017, Munich, Germany
  25. Tsiapalis, D., Zeugolis, D.I. Accelerated deposition of tendon-specific extracellular matrix using macromolecular crowding and low oxygen tensionPodium Presentation at European Orthopaedic Research Society (EORS) Meeting, 13th to 15th of September 2017, Munich, Germany
  26. Djalali-Cuevas, A., Skoufos, I., Tzora, A., Prassinos, N., Diakakis, N., Zeugolis, D.I.Engineering in vitro microenvironments for direct reprogramming of dermal fibroblasts towards tenogenic lineagePodium Presentation at European Orthopaedic Research Society (EORS) Meeting, 13th to 15th of September 2017, Munich, Germany
  27. Pugliese, E., Bayon, Y., Zeugolis, D. Collagen hydrogel as MSCs carrier incorporating tenogenic cues for tendon repairPoster Presentation at European Orthopaedic Research Society (EORS) Meeting, 13th to 15th of September 2017, Munich, Germany
  28. Berdecka, D., Gonçalves A.I., Rodrigues, M. T., Reis, R. L., Gomes, M. E. Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose-derived stem cells. Poster Presentation at European Society for Biomaterials (ESB) Meeting, 4th to 8th of September 2017, Athens, Greece
  29. Tsiapalis, D.V., Zeugolis, D.I. The synergistic effect of macromolecular crowding and low oxygen tension on tenogenic phenotype maintenancePodium Presentation at European Society for Biomaterials (ESB) Meeting, 4th to 8th of September 2017, Athens, Greece
  30. De Pieri, A., Ryan, C.N.M., Rochev, Y., Zeugolis, D.I. The influence of biophysical cues on in vitro stem cell differentiation towards tenogenic lineagePodium Presentation at European Society for Biomaterials (ESB) Meeting, 4th to 8th of September 2017, Athens, Greece
  31. Rampin, A., Tzora, A., Skoufos, I., Diakakis, N., Prassinos, N., Zeugolis, D.I. Engineering optimal culture conditions to maintain tenogenic phenotype of tenocytesRapid Fire Podium Presentation at European Society for Biomaterials (ESB) Meeting, 4th to 8th of September 2017, Athens, Greece
  32. Rampin, A., Tzora, A., Skoufos, I., Diakakis, N., Prassinos, N., Zeugolis, D.I. Engineering optimal culture conditions to maintain tenogenic phenotype of tenocytePoster Presentation at European Society for Biomaterials (ESB) Meeting, 4th to 8th of September 2017, Athens, Greece
  33. Ribeiro, S., Novacek, V., Bayon, Y., Zeugolis, D. Design and evaluation of biodegradable polymeric films for tendon tissue engineeringPoster Presentation at European Society for Biomaterials (ESB) Meeting, 4th to 8th of September 2017, Athens, Greece
  34. Djalali-Cuevas, A., Skoufos, I., Tzora, A., Prassinos, N., Diakakis, N., Zeugolis, D.I. Direct reprogramming of dermal fibroblasts towards tenogenic lineage by cell microenvironment modulationPoster Presentation at European Society for Biomaterials (ESB) Meeting, 4th to 8th of September 2017, Athens, Greece
  35. Garnica-Galvez, S., Skoufos, I., Tzora, A., Prassinos, N., Diakakis, N., Zeugolis, D.Engineering optimal culture conditions to promote adipose-derived stem cell tenogenic differentiationPoster Presentation at European Society for Biomaterials (ESB) Meeting, 4thto 8th of September 2017, Athens, Greece
  36. Vermeulen S., Vasilevich A., Dimitrios T., Dede A., Zeugolis D., de Boer J. Engineering the tendon fibroblast micro-environment by surface topographies. Oral Presentation at European Society for Biomaterials ESB (2017) Meeting, 4th to 8th of September 2017 , Athens, Greece
  37. Vermeulen S.,  Vasilevich A., Dimitrios T., Dede A., Zeugolis D., de Boer J. Engineering the tendon fibroblast micro-environment by surface topographies. Poster Presentation at European Society for Biomaterials ESB (2017) Meeting, 4th to 8th of September 2017 , Athens, Greece
  38. Tsiapalis, DV., Zeugolis, D.I. Tenogenic phenotype maintenance using macromolecular crowding and low oxygen tensionPodium Presentation at Tissue Engineering and Regenerative Medicine International Society (TERMIS) EU Meeting, 26th to 30th of June 2017, Davos, Switzerland
  39. Guillaumin, S., Zeugolis, D. The effect of hypoxia and macromolecular crowding on matrix deposition and phenotype maintenance of human adipose derived stem cellsPoster Presentation at Tissue Engineering and Regenerative Medicine International Society (TERMIS) EU Meeting, 26th to 30th of June 2017, Davos, Switzerland
  40. Berdecka, D., Gonçalves A.I., Rodrigues, M. T., Reis, R. L., Gomes, M. E. Evaluation of tenogenic differentiation potential of selected subpopulations of human adipose-derived stem cells. Poster Presentation at Chem2Nature 2017 Summer School, 5th to 9th of June 2017, Porto, Portugal
  41. François I.,Smith R. K., Dudhia J. Developing strategies to improve the healing of equine tendon using a surgical model. Poster Presentation at RVC Comparative Physiology and Medicine Symposium, 31st May 2017, Royal Veterinary College, United Kingdom
  42. Sivelli G., Smith R. K., Dudhia J. Investigation of synovial fluid on tendon injuries. Poster Presentation at RVC Comparative Physiology and Medicine Symposium, 31st May 2017, Royal Veterinary College, United Kingdom
  43. François I.,Smith R. K., Dudhia J. Developing strategies to improve the healing of equine tendon using a surgical model. Poster Presentation at RVC Post Graduate Research Day, 3rd May 2017, Royal Veterinary College, United Kingdom
  44. Sivelli G., Smith R. K., Dudhia J. Investigation of synovial fluid on tendon injuries. Poster Presentation at RVC Post Graduate Research Day, 3rd May 2017, Royal Veterinary College, United Kingdom
  45. Rampin, A., Tzora, A., Skoufos, I., Diakakis, N., Prassinos, N., Zeugolis, D.I. Engineering optimal culture conditions to maintain tenogenic phenotype of tenocytesPoster Presentation at The Federation of European Biochemical Societies (FEBS) Advanced Lecture Courses in Matrix pathobiology, signalling and molecular targets, 25th to 30th of May 2017, Spetses, Greece
  46. Garnica-Galvez, S., Skoufos, I., Tzora, A., Prassinos, N., Diakakis, N., Zeugolis, D.I.Characterisation of adipose-derived stem cells and optimal in vitro culture conditions to promote their differentiation towards tenogenic lineagePoster Presentation at The Federation of European Biochemical Societies (FEBS) Advanced Lecture Courses in Matrix pathobiology, signalling and molecular targets, 25th to 30th of May 2017, Spetses, Greece
  47. Djalali-Cuevas, A., Skoufos, I., Tzora, A., Prassinos, N., Diakakis, N., Zeugolis, D.I.Development of in vitro microenvironemnts for directing dermal fibroblasts towards tenogenic lineagePoster Presentation at The Federation of European Biochemical Societies (FEBS) Advanced Lecture Courses in Matrix pathobiology, signalling and molecular targets, 25th to 30th of May 2017, Spetses, Greece
  48. Hebels D., Dede A., Carlier A., de Boer J. cBiT – The compendium for Biomaterial Transcriptomics. Poster Presentation at The Genotype Tissue Expression (GTEx) Project, 20th and 21th March 2017, Barcelona, Spain
  49. Sivelli G., Smith R. K., Dudhia J. The past, present and future of treating tendon injuries at the RVC. Poster Presentation at RVC Research Highlights, 30th November 2016, Royal Veterinary College, United Kingdom
  50. Berdecka, D., Gonçalves A.I., Rodrigues, M. T., Reis, R. L., Gomes, M. E. Human adipose derived stem cell-in search of subpopulations prone to tenogenic differentiation. Poster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18th of November 2016, Galway, Ireland
  51. De Pieri, A., Rochev, Y., Zeugolis, D.I. Multilayered tendon-like construct fabrication based on aligned electrospun thermo-responsive nano-fibresPoster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18th of November 2016, Galway, Ireland
  52. Djalali-Cuevas, Skoufos, I., Tzora, A., Prassinos, N., Diakakis, N., Zeugolis, D.I. Engineering optimal culture conditions for trans-differentiate dermal fibroblasts towards tenogenic lineagePoster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18th of November 2016, Galway, Ireland
  53. Garnica-Galvez, S., Skoufos, I., Tzora, A.,  Prassinos, N., Diakakis, N., Zeugolis, D.I.Engineering optimal culture conditions to differentiate adipose derived stem cells towards tenogenic lineagePoster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18thof November 2016, Galway, Ireland
  54. Guillaumin, S., Spanoudes, K., Zeugolis, D.I. The effect of hypoxia and macromolecular crowding on matrix deposition by bone marrow and adipose derived stem cellsPoster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18th of November 2016, Galway, Ireland
  55. Pugliese, E., Biggs, M.J.P., Zeugolis, D.I. Collagen type I scaffolds with controlled surface topography and substrate rigidity for tendon regenerationPoster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18th of November 2016, Galway, Ireland
  56. Rampin, A., Skoufos, I., Tzora, A., Prassinos, N., Diakakis, N., Zeugolis, D.I. Engineering optimal culture conditions to maintain tenogenic phenotype of tenocytesPoster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18th of November 2016, Galway, Ireland
  57. Ribeiro, S.C., Novacek, V., Bayon, Y., Zeugolis, D.I. Optimisation and characterisation of biodegradable polymeric films for tailored tendon differentiationPoster Presentation at Matrix Biology Ireland (MBI) Meeting, 16th to 18th of November 2016, Galway, Ireland
  58. Tsiapalis, D., Zeugolis, D.I. Macromolecular crowding in human tenocyte culturePoster Presentation at Matrix Biology Ireland Meeting, 16th to 18th of November 2016, Galway, Ireland
  59. Berdecka, D., Gonçalves A. I., Rodrigues, M. T., Reis, R. L., Gomes, M. E. Human adipose derived stem cell-in search of subpopulations prone to tenogenic differentiation. Poster Presentation at Gene2Skin and Term Stem 2016 Conference, 24th to 28th October 2016, Guimarães, Portugal